Cobetter Minilab TFF System: A Revolution in Pharmaceutical R&D Process Development - Copure

Cobetter Minilab TFF System: A Revolution in Pharmaceutical R&D Process Development

5, Feb 2024

In the dynamic world of pharmaceutical process development, companies often grapple with significant challenges, ranging from high research and development (R&D) costs to process uncertainties, low automation, and poor reproducibility. Recognizing these pain points as opportunities for innovation, Cobetter has introduced the Minilab TFF (Tangential Flow Filtration) System, meticulously designed to alleviate the hurdles faced in R&D testing for pharmaceutical companies.

Addressing Key Pain Points:

During the initial stages of process development, pharmaceutical companies commonly encounter several pain points that impact their efficiency and success:

  1. High Experimental Operation Requirements and Low Error Tolerance: The Minilab TFF system mitigates the risk of errors by offering a user-friendly interface and precise control over experimental operations, reducing the likelihood of costly mistakes.
  2. Low System Automation: Cobetter’s system introduces automation to streamline processes, reducing manual intervention and enhancing overall efficiency in laboratory operations.
  3. Difficult Data Collection and Limited Data Amount: Minilab TFF addresses data collection challenges by providing a comprehensive platform that collects and records a variety of data, empowering researchers with valuable insights.
  4. High Process Testing Costs: The Minilab TFF system’s small running volume significantly reduces testing costs, making it a cost-effective solution for pharmaceutical R&D.
  5. Yield Control Difficulty and Poor Reproducibility: With its powerful functionality, the Minilab TFF system allows for precise control over yields and ensures high reproducibility, critical for successful process development.

Key Features of Minilab TFF System:

Cobetter’s Minilab TFF system introduces several features that make it valuable for pharmaceutical R&D:

  1. Low Testing Cost and Flexibility: The Minilab system boasts a small running volume, significantly reducing testing costs. Its flexibility allows for seamless adaptation to various laboratory conditions, offering a cost-effective solution for pharmaceutical R&D.
  2. Adaptable Consumables: The system’s compatibility with two types of consumables, hollow fiber membrane or membrane cassette, provides researchers with the freedom to choose based on specific experimental requirements.
  3. Versatility Across Brands: Minilab TFF stands out by offering compatibility with a variety of different brand products, ensuring researchers have the freedom to choose the best components for their unique processes.
  4. Powerful Functionality: The system’s powerful capabilities enable a variety of process operations, making it a versatile tool for researchers in the pharmaceutical industry.
  5. Comprehensive Data Collection: Addressing the challenge of limited data collection, the Minilab TFF system can collect and record a plethora of data, empowering researchers with valuable insights for more effective decision-making.
  6. Tailored for R&D: Specifically designed for basic process development at the R&D end, the Minilab TFF system aligns with the unique requirements of pharmaceutical research, ensuring efficient and effective results.

System Components:

The Minilab TFF system’s flexibility is evident in its components, which can be freely combined to adapt to various usage environments. Key components include:

  1. Hollow Fiber Options:
  •  Mini 30cm / Mini 60cm
  •  Minilab 30cm / Minilab 60cm
  1. Cross flow cassettes, Consieve UET Options:
  • Consieve UET 0.01m²
  • Consieve UET 0.1m²
  1. Maximum Flow Rate:
  • Main pump – 3400 ml/min
  • Auxiliary pump – 480 ml/min
  1. Compatible cross flow Holders: 0.01m²
  2. Space Requirements: Benchtop
  3. Minimum Operating Volume: 20ml
  4. Standard Instruments:
  • Pressure transmitter
  • Balance
  1. Tank Volume: 500ml
  2. Self-Control Mode:
  • Constant TMP control
  • Constant ∆P control
  • Equal volume washing rule
  • Continuous concentration
  • Inline NWP
  1. Power Supply: 220V
  2. Applicable Applications:
  •  Lab R&D
  •  Process development


Cobetter’s Minilab TFF Tangential Flow Filtration System emerges as a revolutionary tool for pharmaceutical R&D process development. Its innovative features, adaptability, and comprehensive functionality, address the industry’s pain points and sets a new standard for efficiency and reproducibility in research laboratories. The Minilab TFF system is not just a tool; it’s a strategic ally for pharmaceutical companies navigating the intricate landscape of drug development. By embracing this cutting-edge technology, companies can unlock new possibilities and expedite the journey from R&D to successful drug production.